When there are little or no medications/vaccine, I think that the most beneficial things for the human body is sleep. Methodically speaking, there are steps you can take against preventing a virus from reproducing and build up your immune system responses. We all are aware of how sleep is beneficial; some biology of immunology’s is required to understand the mechanism behind sleeping and how lack of sleep affects our immune system. Sleep studies have revealed the science behind how the immune system lowers any chance of foreign replication. In the human body, in the case of viral infections (COVID-2019), we have antigen presenting cells (APC) that attaches to the infected cell, these antigens are presented on the outside of the cell and interacts with the CD4+ also known as T helper cells. The CD4+ attachment is the most crucial part and most beneficial to the human immune system, because this is the site where the antigens will attach and releases the interleukin-12 (IL-12) cytokine, that enhances the signal of CD4+ signal, who also stimulates the CD8+ (killer T Cells) and B cells at the same time and that produces antibodies that attach to the antigens and neutralize them. Most importantly, there is an inhibition caused by Gα s-coupled receptor signaling and sleep regulates integrin activation of human antigen-specific T cells (Dimitrov et al., 2019). Which means when there is binding in wakefulness, of isoproterenol, epinephrine, & norepinephrine to Gα s-coupled receptor on the killer T cells, that cause an inhibition of beta 2 (B2) integrin proteins, which allow binding to the effected cells. This makes it where there is no binding from the T killer cells to the foreign invaders and the virus can reproduce or evade the immune system.
AGSC 5110 Research Methods 